kopano smtps port 465
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Many different configurations are possible.
What distribution are you on?
How do you plan on authenticating your users? (ldap, or kopano db in mysql)
https://kb.kopano.io/display/WIKI/Postfix
You’ll also depend on proper SSL setup. One way to do it, using Letsencrypt.
EDIT:
(Assuming you are on latest current Ubuntu distro)
https://ubuntu.com/server/docs/mail-postfix
And lookup postfix letsencrypt guides, there are so many out there… I suggest as a building block to start with initial self-signed certs, once you have smtps auth working proper, then move your way up with letsencrypt.
Valid SSL cert is an important part, especially for Outlook.
Marc